Slay the Spire: Ironclad Any% in 5:32 [Former WR]
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As it turns out, my previous record stood for less than a day before being snatched back by AntiFlame. On the other hand, his record was even shorter lived. This run crushes not only my previous record, but also my previous sum of best. I'm pretty sure it also contains at least 15 seconds of time loss in Act 1 alone, so I feel pretty confident that sub-5 will arrive eventually.
This run stood as WR for a whopping 2 days before being beaten by AntiFlame (by 1 second).